Apolipoprotein A1 (Apo A1) is the major structural and functional protein component of high-density lipoprotein (HDL). Apolipoprotein A1 FS determines the Apo A1 concentration in serum and plasma. Determination of Apo A1 is used for cardiovascular disease (CV) risk assessment. Studies showed that especially the Apo B/Apo A1 ratio is a strong predictor for CV diseases